Immunological evaluation

Immunological testing is a key part of diagnosing infertility, especially when no clear causes can be found or when there have been repeated miscarriages. The immune system plays a crucial role in the implantation and maintenance of a pregnancy. In order for a fertilized egg to be accepted, the maternal immune system must find a balance: on the one hand, it should not reject the embryonic development, and on the other hand, it should continue to provide protection against infections.

Disturbances in this balance can lead to problems. These include the presence of autoantibodies (e.g.: thyroid antibodies, antiphospholipid antibodies) or dysregulation of certain immune cells such as natural killer cells (NK cells). Such changes can make implantation difficult or promote repeated miscarriages.

Immunological diagnostics are performed using special blood tests that examine antibodies, cell activity, and inflammation parameters. Depending on the findings, various treatment approaches are available, such as the administration of immunoglobulins, cortisone, or anticoagulant medication. The aim is to regulate the immune system in order to improve the chances of pregnancy.

Immunological testing therefore complements other diagnostic procedures and offers couples with repeated failed attempts or unexplained infertility a valuable opportunity to identify previously undetected causes and treat them in a targeted manner.