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ERA-TEST FOR INFERTILITY: ENDOMETRIAL RECEPTIVITY ARRAY


Around a quarter of patients with repeated implantation failure have a ‘shifted implantation window’. Typically, an embryo will implant exactly 120 hours after the hormonal rise in progesterone.

The so-called implantation window can be found by undertaking an ‘Endometrial Receptivity Array Test’ (ERA-TEST) in our Kinderwunsch Institut in Linz. During the ERA-Test, undertaken at the time an embryo transfer would take place, a small tissue sample is taken from the lining of the uterus with a fine, flexible tube (pipelle) and analysed in the laboratory. The biopsy is absolutely painless and uncomplicated for most women.

Results:

If the uterine lining is found to be ‘receptive’, this means the embryo can implant exactly 120 hours after the progesterone surge. Embryo transfer can be performed in a later cycle 120 hours after starting progesterone.

If the lining of the uterus is found to be ‘non-receptive’, this means that the ‘implantation window’ has shifted. In this case, a new, individually calculated window is suggested (for example on day 4 or 6 after egg retrieval).

If the ‘personal implantation window’ of the patient is known, the embryo has a better chance of successful implantation.